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The titanium dioxide market fluctuated in the first two quarters of 2023. These pricing patterns resulted from poor demand and reduced intakes from the downstream industries. Amid the slow demand, the manufacturers were forced to reduce their outputs. With rising inflation rates, production cuts gradually increased. Given the economic downturn, the labor strikes further affected the market dynamics, thereby exerting pressure on the pricing fundamentals.

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When used in food specifically, titanium dioxide is known as an additive called E171 and can be found in products like candy, chocolate, coffee creamer, cake decorations, chewing gum and even vitamin supplements. E171 is often used as coloring additive in foods, to lend the processed item a natural whiteness and opacity — such as in Skittles candy, where it's used as a white base to help give the candies their signature bright, colorful hue.

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In a 2019 study published in the journal Nanotoxicology, researchers recreated the first phase of digestion in mice and fed them titanium dioxide, then examined whether accumulation occurred in the organs. Researchers wrote: “Significant accumulation of titanium was observed in the liver and intestine of E171-fed mice; in the latter a threefold increase in the number of TiO2 particles was also measured. Titanium accumulation in the liver was associated with necroinflammatory foci containing tissue monocytes/macrophages. Three days after the last dose, increased superoxide production and inflammation were observed in the stomach and intestine. Overall, [this] indicates that the risk for human health associated with dietary exposure to E171 needs to be carefully considered.”

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In 2021, the European Food Safety Authority concluded that titanium dioxide is no longer safe in foods due to the same concerns over nanoparticles. As a result, titanium dioxide is now banned as a food additive in the EU. Although studies have shown that the absorption of ingested titanium dioxide is low, evidence suggests that titanium dioxide nanoparticles can accumulate in the body over time. Health Canada deemed it safe in 2022 but noted concerns. Unlike their European counterparts, Canadian officials did not consider studies performed with titanium dioxide nanoparticles alone. 

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